GA reflected changes in glycemic control in less than 2 weeks, 11 weeks earlier than HbA1c. A just-published multi-author article in the Journal of Diabetes Complications concluded “glycated albumin is superior to glycated hemoglobin for glycemic control assessment at an early stage of diabetes treatment,” based on comparison of results from four hundred ninety-nine patients in 10 hospitals in Beijing. The aim of the study was “to determine whether serum glycated albumin (GA)
A recent report in the Journal of Diabetes and Its Complications investigated whether glycated albumin (GA) and HbA1c could “represent glycemic profiles in hemodialysis.” The study on patients with hemodialysis determined that “HbA1c correlates [with] the average glucose more than GA but underestimates it. [Therefore], a correction formula of HbA1c can be developed as an appreciable marker.” Also, even though average glucose is reflected less accurately with GA than with HbA1
A research article published in PLOS One tested “the possibility that measurement of serum glycated albumin (GA) [could] assess the need for” an oral glucose test (OGTT) better than HbA1c. The six yearlong study concluded, “In the diagnosis of diabetes, serum GA measurements can be used to determine the need of an OGTT.” Type 2 diabetes can be diagnosed by either HbA1c results or an OGTT. Due to its time-consuming nature, however, the OGTT is only used as a secondary measure.
An article in BioMed Research International “investigated whether GA increases with time relative to glycated hemoglobin (HbA1c) and the association between GA and beta-cell function.” The study concluded that glycated albumin levels do increase relative to HbA1c over time. 340 type 2 diabetes patients were analyzed in order to study the changes and characteristics of glycemic indices (GA, HbA1c, ∆GA/HbA1c). The “glycemic indices decreased and maintained low levels at the bas